Height Information Aided 3D Real-Time Large-Scale Underground User Positioning

Due to the cost of inertial navigation and visual navigation equipment and lake of satellite navigation signals, they cannot be used in large‐scale underground mining environment. To solve this problem, this study proposes large‐scale underground 3D real‐time positioning method with seam height assistance. This method uses the ultrawide band positioning base station as the core and is combined with seam height information to build a factor graph confidence transfer model to realise3D positioning. The simulation results show that the proposed real‐time method is superior to the existing algorithms in positioning accuracy and can meet the needs of large‐scale underground users

Height information aided 3D real‐time large‐scale underground user positioning

Abstract Due to the cost of inertial navigation and visual navigation equipment and lake of satellite navigation signals, they cannot be used in large‐scale underground mining environment. To solve this problem, this study proposes a large‐scale underground 3D real‐time positioning method with seam height assistance. This method uses the ultra wide band positioning base station as the core and is combined with seam height information to build a factor graph confidence transfer model to realise 3D positioning. The simulation results show that the proposed real‐time method is superior to the existing algorithms in positioning accuracy and can meet the needs of large‐scale underground users

Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association

In a variety of yeast cellular pathways, the Ste50p protein regulates the kinase function of the mitogen extracellular signal-regulated kinase kinase (MEKK) Ste11p. Both Ste11p and Ste50p contain sterile alpha motif (SAM) domains; these are interchangeable, and can be replaced by other protein -interacting modules. Furthermore, the function of the Ras association (RA) -like domain of Ste50p can be mimicked by a plasma membrane recruiting signal, and direct plasma membrane targeting of Ste11p bypasses the requirement of Ste50p for Ste11p function. Thus the regulatory role of Ste50p requires both the N-terminal SAM domain to bind Ste11p and the C-terminal RA-like domain to direct kinase localization. We have identified Opy2p, an integral membrane protein that can interact with Ste50p, as a new component in the Sho1p -Ste11p/Ste50p signaling branch of the high-osmolarity glycerol (HOG) pathway. We propose that Opy2p can serve as a membrane anchor for the Ste50p/Ste11p module in the activation of the HOG pathwayNRC publication: Ye